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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc66aafe9f77875478be2004346b84333f8d9fe2686f8bb8da2a24de3ad77cbc' 
  AND token = '+5XMjaB6isQKUEcTBryf+Y3rExTAtvD4rnvgRT5xbuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}