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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be628a21fbbbed13e2d7812d29505ccad2ba0467bce57c1b2aecdcdbf607e24d' 
  AND token = 'CPFFtCNbBq34MKOhu32Z3CJ8kKecCyhRjAYxhaaZ2O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}