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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dbbd7d4284651f5287bf1913a07f05a28e7fc4d58c14e5f0e44cac0f1a8ff24' 
  AND token = '7FCOCSp/hOOABeZKJOG5mGxMInw318kB66UwonTJl4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}