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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04557d0e87e6e70876d7e5051ff0faeff7b07e50fb05a867fc2d956b9c4cc455' 
  AND token = 'oVOYH21T3O6Uh+5tQaya7TxtjYx/DwkEIM9jbrlnJPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}