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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42221ab7ab1ed7f9729281df1b5894ac4d37026399d23556f38c0e58ce28eb29' 
  AND token = '3JJMi4spIM7rXSCPMv6fGFPqAq9iuHQ3AOrPEV/KmOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}