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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd16bb4b6d3058a3634f915436c175b1a93134f6015992ce0ce9ae5a264a3274' 
  AND token = 'SAnECgRx6z2DeYsPKGqPx75WIu+dzliot8Fq30uLIgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}