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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8fb106973b74c6e0676aa5c4b16a8d4d8493dcc17b4c26013b8c018004958d' 
  AND token = 'MqHh3FuhPpEj7JU2fdrq0fOlbbW1SZ68X04AWoCRdBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}