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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a821e4c52bd35ba65c5e00385284ea7c1a765ac2f02372e998dbe8e4c81479' 
  AND token = 'rq6s0YkPgGRYGt3AHIZE96E0btuhS7mRg+296B5lZz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}