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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cea31de9f2296b01ccf521c60cb8d43fb085dccb06bbcc3d9b7fcd4773886330' 
  AND token = 'Ay/hE7CddAbNNIi2sRsEU5LfboR1b2zuA7xLz0RUfaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}