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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e7384bcfd4c1f5d212d452f799e2a17f3f5041e0908770330c447b24aa5d8b8' 
  AND token = 'XBQcWb7+yAp/POD/PTZxVtrOH9OO6ak/yyGhOL2DVDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}