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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a17d509c37cc449d4859c2032e8563c1cffe1f5837c04e5f0bcad5483435b390' 
  AND token = 'e3IjxGVKx85tVkMSdO6+ahRXwZUrI1NBuX42w0n9fJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}