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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf0508751ae2c270c3f77e6c0a3e1d83925f57292708c2abec497ed1f0ac54b' 
  AND token = 'a5R//0ZOauVQ8xW0hJD6h9XkSDo24Vu3PXGlTrt5RF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}