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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d3bd37130283110f146c689a707018b5e86017ad80f8c333536f22814c978a' 
  AND token = 'v5mps7YsIwJfGquGIT/KexPnqn73lH+1JUt0tpdeUz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}