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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a98fe1794d419dd4a4e270519fe8238b86f9f4c7f0f6049f2ccabb93acad0b' 
  AND token = 'sg/tT9ch2hZNNDpq/YVaNik0xcGT+bmEfNDDcPRYpWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}