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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f60147ab2fd421d7a0bb12097069277233d9914c0a45ddc83e3d6c14ad265743' 
  AND token = 'QeVv63dCgo3hl35hv0tHfJ7eSJROf0mm1NEfzeB/WIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}