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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2fbaa8ab9a28fd3238c4c9fc39f0bd8559c2c99efcf2810c9d9f5aa9ad950c' 
  AND token = '2svw9KmfmvrLtVem2GJcwhRPK+7ihiSJj1zsy6DLLpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}