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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601f0810167d09a586734386d730946c6e762082037097f5e74ad93665ad1c4c' 
  AND token = '9YCtks4szVIrZAanN9TdLy4OwMnKb4hT2Jdqfd0QWdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}