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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526a9995b523ccddc48763b033af3a62803cfc48a0950130ad20fe4ee4c46aed' 
  AND token = 'xpNVlYkrnqzAeIZk6UCfhmW5bc+a1WuN/NxuNTcb9m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}