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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ef539c1682f597474cbf551e18464729a7bb2199c2d4ebda9cbf9709519ae9' 
  AND token = 'Kmk/gPQSv8phbuX5kZyEUINobV+Rag/3Pg7Ga7DcKMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}