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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75746749a8cb5f28a227ed5852119949efe5a622f858c47b9d776c77b4a9f3f1' 
  AND token = 'zVqtHpXYiwQa6acn3o9ar5QWuYsaNZ9lDjt0BwBs2PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}