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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3d50a4e341a94aa71787b579d4c5b1671aa12a59c258c58274658ccda98310' 
  AND token = 'rvX3N58cH49KgXNQT1dlQ/vKFCqo7sepv1CvUJ/EO9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}