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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0128a76150ef77ae2b6bb06b4dd9f3c9186b3d1cceeb8c2c356d99cae337ff' 
  AND token = 'iHj0K+6dJ5ji9mvaYOMTYqvUbSo3MW7T9cXe/cy5cGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}