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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dacf1d31f3d232d9fe6999070ca432023a25ceb2f4e436a97540c3b4100423ee' 
  AND token = 'DSt7yCIOFnTpFg6dsBySMtkNQ958T2/CQbQGAOB7ny4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}