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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c7a3508ee7e809d5a64b0464e1478134fb95cb3348e6f55df00a3a8b9c7a3ec' 
  AND token = '6vhX1RcYG0R5vyyA3PUvlYMgZnZO8FgbnsxoMr4iMII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}