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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b0c098bfd824f005c7d87794c51a3acfa553339a2c7028e1810b77cbeb7f71' 
  AND token = '1NVQ2H0K7Wsn2Ch+4qLM8sFghQ/9OUyQQhbjAtsI4rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}