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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45dcdd4b2611f4cc82761cf762961f80f53f7bd82352bdfffcd94845e821a1c8' 
  AND token = 'p+oXi4awq6MqsSuBqn+ohH374kv9A4xpSM9ywH1PDcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}