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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbcb34a5d46343317d7c1a25e502645104153bd9f2955cf4816e8f8e5ee1284' 
  AND token = '1E8Zvj7l+ylzbVdcwKKrazEQKMHoG7EV5Shuhsc5XsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}