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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a679df354c5d463bdbfbfe23fba05c04930e1a0766e647e541c90f389ca58af' 
  AND token = 'aKbSoOASqWYVs+SS5sUFKUQpV4Ol6YoTwz8lArSW7u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}