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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb9167644d1b53170135bfed533cc97b616126114ef6a2bad91258cf3f21f3d' 
  AND token = 'rMeFxq8M4xPxAv+T/K2l8oaNcKqfHPFo9VmtdPvnViw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}