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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18d6de3d97dd489fd52732ccaf7ae545714f34f831f5d6496a61198a6e6a388' 
  AND token = 'Rz5B3sDhDsCJqEjJEkmSHYmaQgHqZKJri5rSir0S2M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}