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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc835cf4c6649a744880126fd826c1e722d5be7094b9b6f56b8b92b8b560649' 
  AND token = 'I7tmr8Ll57nEacq3wk94/rSPUhevZ6Ti6nd0iTjevms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}