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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e351def378b2615adc489bc8e4c5b432153c2f7b7b483dfbb433788c334a29f2' 
  AND token = 'cOh/p3SABygx3LHRNO3L4xcqUixBb0Xx8jvEb4zMtQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}