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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f377071ac93efe16493b85b3acad0eec332258e59aa2c2cdd4b4299e0150a4' 
  AND token = '+H4FFYkJMldu/EcN7f4O/biY0BX81GT4Gsr6wzKqRdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}