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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02c4d114f126cf84361dfccbaf264fcf18f80f7adb11545d1643803094755a3' 
  AND token = 'BL5bAk17x0CPr5VFvx4B2jqfH3JmdFFwgBAybwiF7nU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}