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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4d983acf988defb1b5802084d7a737f1507c190aed1ecc6df13e7323640806' 
  AND token = 'H1PMy+vw61lHOUhGSc+W/r3bXRGFqVSfuEbNmTwhx0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}