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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a5a9a3deb8f08e7448e5a5391b7be32980f0a16cd568d8d5155d7c38496ff0' 
  AND token = 'bbLqbOrpj2nAqgESD6qTJHO03zSpTj4IsGIGKDiZ9qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}