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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ccbd069e17fc2e2be759aabdb02b48c6f716aa54499ee580781480b17bd0ef0' 
  AND token = 'tf/sQf3i1muWU2ZR2Py8d3a3S8v24vFGRP2UNlNXgkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}