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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fea4314fc77760bbd9729f78da03894049946e63c0b32c7828f6aa4d9c0fd96' 
  AND token = 'G3llOEADd5UXrIF0r4UV/waNXXj9VPFbz66PyPic7vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}