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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022c68bada94cfc8032248f4adfeabaeb1c54225dc65dee1b4c63c0a592947b6' 
  AND token = 'K9MSOnPOqoJ3GMalP2TtN+S1WB6uuuhZNcA2jF+hHm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}