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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb851be7a63307f0c96c4b458b9825086ff7000e42f35a2c5743108a29c2cdf' 
  AND token = 'AW8Ui31/ynMuBotIsyANMuRZXXkwXFVTYov7SBT3wTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}