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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36221c4868a2a2e84ac098a2dc146200593f59ad4a5bb258ee212c478dd62086' 
  AND token = '1TqSDiqroH/OUfoLhLjLepxuP8Pt7CtMjneGtUz70rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}