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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85f34fbc9540b34d58b85d86a0aee45dd8e7330557b91fa05c045a34677d42d4' 
  AND token = 'bDO9ga/hnFlsnRzIAssBD+6p3H/0M0FliYNXSuC5vkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}