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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b855e68c57d84f5a69dd82668dcd3774527b1614a80ae53993b461c25b0f7d' 
  AND token = 'Wc238OVO0cy/Qhu/TW+aYvdeXZPWVoDdn2CK/Lj2fwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}