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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb9319810a1c4769b2f04d47c4d990ddd9c8f624f87afe87b99480dd373dc32' 
  AND token = 'EUy+Vn00CWDPH9AFNOTk/FMZRoMOAxlz/Q9F2Fk7WDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}