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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55a2e67de919e511a0313eb235944129dbb3dba5d7a22152c963a9aa615c760a' 
  AND token = 'fkD5oncNn+dRvwyAVuJcH/A+Du1sJrts8CAGJiBUnz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}