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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a301f4d87493757a2ae104e50ab88236ea72a8dce967be461e32564a325eea20' 
  AND token = 'Ji/70MirfI63isdxZTo3YTTEkcxmPKGdhMyQpGEG9Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}