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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e2d1a40bd376b1784d203aa8947daaf63ec39ab0b077c5369ee6b736f7d9e50' 
  AND token = 'DZZUkd/7qT6RfDid2X/dKipRU+SnVpQx/0Gkbn2PnRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}