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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd343d3d3e752e1906132ccc8549eae46e697851212a8462d3d74599ee0f7dce6' 
  AND token = 'Yf7mro/t25AoUsgO+P6vCe+hx3i/T6CQ3aDEdjBO19Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}