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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ece91adb61f6c0b40199afb05d9217ce980492820023ad9d1c6c59e13f301f6' 
  AND token = 'MTrcZ1Zdx2kIEeUUbwK6CVBluBOv801U0VhjEmHE9mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}