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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2100e5cf66d8afcf2ffca330bc272f6ca975ccfbbb5d325d420ddf1c50562f8' 
  AND token = 'QuI/+Eq8YyuI2cKHN58zoh2Opxgk2XoD7IMG4CmUvqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00092

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}